HPV28 Detection

Anyplex™ II HPV28 Detection simultaneously detects 19 high-risk HPVs and 9 low-risk HPVs using DPO™ technology and melting curve analysis method of TOCE™ technology. 40 of HPV genotype cause infection in the genital area; they are classified as low-risk (HPV6, HPV11, cause of genital warts) and high-risk cause of cervical cancer. HPV16 and HPV18, a high-risk HPV genotype, accounted for more than 70% of the cause that leads to cervical cancer. This product can be used as a screening for an early diagnosis of cervical cancer by detecting the infection and differentiating the gene type of 19 high-risk HPV and 9 low-risk HPV infections accurately.

Anyplex™ II HPV28 Detection has been specifically designed to address this unmet medical need through the simultaneous detection, identification and quantification of 28 HPV distinct genotypes (19 high-risk HPVs and 9 low-risk HPVs) contributing to cervical cancer and/or sexually transmitted infection within 6 hrs. It provides effective result by including internal control which checks the whole process from nucleic acid extraction and PCR.

Features:

• Detection and identification of 19 high-risk HPV and 9 low-risk HPV from a single real-time PCR

• Multiplex real-time PCR with high sensitivity and specificity due to the utilization of DPO™ and TOCE™ technologies

• Quantitative analysis by cyclic-CMTA

• Amenable to automated sample handling and assay systems

• Application of UDG System to prevent carry-over contamination

• Applicable to Whole Process Control

• Convenient analysis of results available through Seegene Viewer

Analytes:

19 High-risk HPV genotype: 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 69, 73, 82

9 Low-risk HPV genotype: 6,11, 40, 42, 43, 44, 54, 61, 70

Specimens:

- Cervical swab specimen

- Liquid based cytology specimen